Published On: Wed, Dec 11th, 2013

Medicinal Uses of Mannitol

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Source and Properties of :

Mannitol is a hexahydric obtained by isolation from manna or sea weeds. It is also obtained from mannose by reducing chemically. It is also known as manna or D-mannitol. It is a white, crystalline, non hygroscopic powder with sweet taste and without odour. It is freely soluble in water. The crystals are orthorhombic prisms. They are optically inactive but slightly laevorotatory.

English: Output of PubChem's program PC3D for ...

English: Output of PubChem’s program PC3D for D-Mannitol as linked from PubChem. (Photo credit: Wikipedia)

Uses of Mannitol:

  • Used as an excipient for tablets
  • Diluent for liquids
  • Used as stabiliser, thickener and nutritive sweetener
  • Used as texturizing agent
  • Nutrient
  • Diagnostic agent
  • It is not given orally as it does not get absorbed from the gastro-intestinal tract
  • If it is given in the form of injection, it is not metabolised and is eliminated by glomerular filtration, hence used as a diagnostic aid
  • Used as an osmotic diuretic
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